HIV superinfection (infection of an HIV positive individual with another strain of the virus) has been shown to result in a deterioration of clinical status in multiple case studies.However, superinfection with no (or positive) clinical outcome might easily go unnoticed, and the typical effect of superinfection is unknown.We analyzed mathematical m
Emphysematous pyelonephritis is an acute necrotizing infection with gas in the kidney that portends a poor prognosis.Patients present with sepsis, requiring fluid resuscitation, glucose control, and broad-spectrum antibiotics.Surgical intervention ranges from relief of urinary obstruction (nephrostomy tube or stent), percutaneous drainage or Pocket
Abstract Increasing evidence indicates that Nrf-2, named the nuclear factor-erythroid 2-related factor, may perform anticancer function.In this study, a series of novel substituted phenyl- (3-methyl-1H-indol-2-yl)-prop-2-en-1-one (indolyl-chalcone) derivatives were synthesized and their effects on Nrf-2 activity were observed.We found that compound
Facial multiple miliary osteoma cutis is a variant of osteoma cutis usually occurring in women with a previous history of acne vulgaris.Successful ablative laser treatment has been reported using both plush toy CO2 and Er:YAG lasers among other invasive treatment modalities, like surgical removal.We report a patient with biopsy-proven facial multip
In Vietnam where alcohol use is culturally normative and little treatment is available, persons living with HIV (PLWH) who consume alcohol at unhealthy levels are at greatly increased risk for negative health outcomes.We describe the first systematic adaptation of 2 evidence-based alcohol interventions for use in Vietnam: a combined motivational en